https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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Our team scientific tests bacterial cell division and it is aiming to constitute a ‘base up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
Being a individual, I hold the biblical assignment to examine and use almost everything in generation for the benefit of my neighbour. I don't practical experience any conflict in between faith and science. Quite the opposite, my faith stimulates me to do science, to get open up-minded on the planet.’
2007, first true-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of ends of microtubules; and solved the system of biosensing with carbon nanotubes
2015, discovery that condensin is actually a really flexible protein structure; and to start with detection of DNA knots employing nanopores
The coiled-coil from the human Rad50 DNA maintenance protein is made up of particular segments of amplified versatility
MATLAB codes for information processing are offered at . Julia codes utilized for numerical simulation are available at .
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative trend
Comprehension elementary processes regulating the spatial and dynamic organisation in the DNA in Dwell cells.
‘The fantastically delicate way by which elements in mother nature purpose never ever ceases to amaze me. If we remedy https://www.ceesdekker.net the puzzle of how lifestyle arrived into currently being, I count on that my amazement in the complexity of creation should have greater and with it my awe to the greatness from the Creator.’
Example (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is revealed in grey, the rim from the pore is highlighted in red, in addition to a 3D rendering with the motion from the DNA rod is exhibited.
Afterwards we spoke once again briefly mainly because Dekker felt that our dialogue of his religion speedily grew to become purely philosophical, While Furthermore, it concretely will help him in his operate.
Visualization of unstained DNA nanostructures with Highly developed in-aim transmission electron microscopy procedures
Sound-state nanopores have confirmed for being a astonishingly adaptable probe for solitary-molecule Evaluation of DNA. I will describe many of our the latest conclusions – precisely DNA knots – and our initiatives to develop the capabilities of sound-state nanopores even further, in the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.